![]() ![]() Under these conditions the traditional subtraction of Vdm from Vdn leads to underestimation of Vdp. However, differences in the exact way of measuring this space result in clinically significant different results and, therefore, debate remains about the true value of this measured parameter.Ĭopyright © 2023, StatPearls Publishing LLC. When physiological dead space ( Vdp) is calculated for a patient who has alveolar dead space, e.g., after pulmonary vascular occlusion, less than the full volume of attached mechanical dead space ( Vdm) appears in the measured dead space ( Vdn ). Indeed, it may serve as a prognostic factor in patients with acute repository distress syndrome (ARDS) who require ventilation. Physiological dead space is the combined volume of anatomical dead space and dead space resulting from the air that is ventilated but not perfused. ![]() This phenomenon has clinical significance because, both in healthy and impaired lungs, properly calculating and accounting for this non-physiological space is important for the proper respiratory care of ventilated patients. This is therefore termed anatomical dead space as it serves no respiratory function. Anatomic dead space is an important phenomenon in respiratory physiology whereby, owing to the fact that upper airways do not function as locations for gas exchange, and because of the tidal nature of ventilation, there is always a fraction of the inspired air that does not perform a physiologic function of exchanging carbon dioxide for oxygen. ![]()
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